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Lycopene
Tomatoes, pink grapefruit, watermelon and guavas contain the antioxidant carotenoid known as Lycopene.
Recent research has shown that Lycopene can inhibit prostate cancer cell growth; however, scientists are still attempting to fully understand the molecular mechanism involved in how Lycopene stops the reproductive cell cycle and induces programmed deaths for cancerous prostate cells. Scientist do know that Lycopene halts the reproductive cell cycle and inducing apoptosis because the carotenoid possesses two unique chemopreventive features:
1. Lycopene interferes with cancer cells by regulating the signals among sex-hormones and preventing the growth of cancer cells.
2. Lycopene disrupts DNA synthesis in growing prostate cell cultures as well as protects healthy DNA from damage.
In an early human trials, Lycopene improved post-surgical survival rates in patients with advanced prostate cancer, reducing levels of PSA, and shrinking both the primary tumor and metastases. More recent, large-scale studies of men with prostate cancer showed that lycopene—alone or in combination with phytosterols and antioxidants—slowed and even halted rising PSA levels. In a 2008 human study, lycopene demonstrated a reduction of the disease progression in men with BPH.
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